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The timing of HRT initiation matters (earlier is generally better, ideally within 10 years of menopause onset) [9]
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Genes associated with glucose metabolism, including fructose-bisphosphatase 2 (Fbp2), pyruvate carboxylase (Pcx), and 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Pfkfb3), have been identified as direct AR targets
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