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The peptide's extraordinary potency, active at concentrations seven orders of magnitude lower than BDNF itself, suggests highly specific receptor interactions rather than broad pharmacological effects
According to a new study published in Diabetes, Obesity and Metabolism, GLP-1 drugs made food taste sweeter and saltier, which led to reduced appetite, increased satiety, and fewer food cravings among those who used the drugs
These include: Enhanced glucose-dependent insulin secretion Suppressed glucagon secretion Slowed gastric emptying Increased satiety via central hypothalamic action This results in both glycaemic improvement and clinically meaningful weight loss
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