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Change history 28 May 2026 A Correction to this paper has been published: References Woodby B, Penta K, Pecorelli A, Lila MA, Valacchi G

Unlicensed peptides like BPC-157, many growth-hormone secretagogues and biohacking blends do not hold MHRA licences so selling or promoting them for human use risks breaching the Human Medicines Regulations 2012 and falling foul of both MHRA enforcement and GMC expectations on prescribing unlicensed medicines

Supplementation may also be considered where appropriate

The combination of GIP and glucagon receptor activation appears to produce additive benefits for liver fat reduction and metabolic health that neither receptor achieves alone