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Common Side Effects: Like all medications, GLP-1/GIP injections may cause side effects, most of which improve over time: Nausea, vomiting, or stomach upset Constipation or diarrhea Reduced appetite or early satiety Worsening reflux Rare: gallbladder issues or pancreatitis Your provider will monitor you closely to minimize risks and adjust your dosing plan as needed

The stronger action of retatrutide might work better for them

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However, what makes the study especially notable is the emergence of evidence that semaglutide improves metabolism and reduces inflammation, providing heart benefits beyond those stemming strictly from lost weight