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Key Specs Peptide class: amylin analog Research context: metabolic and appetite signaling References: PubMed [1,2] Referenced Citations PubMed, Cagrilintide pharmacology: PubMed, Amylin receptor signaling: Amylin Receptor Signaling Research focuses on how cagrilintide engages amylin receptors involved in appetite control and gastric signaling pathways [1]
In the connection to inflammation, we showed that elevation of pro-inflammatory cytokine IL-6, increased anxiety at the lightdark test, and smaller hippocampal volume characterized at baseline (before any applied stress) those mice that become susceptible after social defeat stress (SDS) with social withdrawal and impaired transcriptomic-wide changes in ventral dentate gyrus, and that administration of LAC promoted behavioral resilience at the SDS paradigm in this susceptible phenotype [27]
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Normal muscle function
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