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The original STEP 1 trial reported participant-rated physical functioning, but STEP 1 did not measure DXA body composition or directly test strength

Abdulmalik et al., demonstrated a significantly increased expression of collagen and sulfated glycosaminoglycans (s-GAG), as well as the expression of tendon-specific genes, in Ex-4-treated hMSC compared to both untreated and insulin-treated controls [14]

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