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Anemia can lead to weakness and fatigue
In addition to energy production, vitamin B12 is essential for maintaining the health of the nervous system and red blood cell production
[4] For example, biotin-dependent enzymes facilitate the conversion of pyruvate to oxaloacetate (an important step in gluconeogenesis), the synthesis of malonyl-CoA from acetyl-CoA (the first step in fatty acid biosynthesis), and the catabolism of certain amino acids into Krebs cycle intermediates
Conditions such as leukemia, myelodysplasia, and lymphoma can also affect bone marrow function, leading to thrombocytopenia
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