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For pure weight-loss endpoints, retatrutide outperforms semaglutide by roughly 9 percentage points at peak dose: 24.2% versus ~15% mean body-weight loss at comparable durations [3][4]
The financial math often works in favor of GLP-1 treatment when you factor in reduced food spending, lower healthcare costs from weight-related conditions, and improved quality of life
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doi:10.1016/S2213-8587(17)30092-4 Pratley RE, Aroda VR, Lingvay I, et al
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