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459 Similarly, leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2), a protein linked to PD, localizes to MAMs, where it enhances PERK-mediated phosphorylation of PARKIN, MARCHF5, and mitochondrial E3 ubiquitin ligase activator of NF-B (MULAN), thereby facilitating the ubiquitination of MFN2

Besides, studies on pregnant and lactating women were excluded