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Description

Firstly, the development of SFN is limited by its water-insoluble and unstable properties

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However, for many plan sponsors and consultants, the reality isnt always clear-cut

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In 2019, Crizanlizumab, a P-selectin inhibitor, was approved by the FDA for the prevention of vaso-occlusive crises in patients with sickle cell disease (Figure 1)

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Clinical trials show patients losing 15-25% of their body weight

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