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These include promoting insulin production, suppressing glucagon secretion, reducing hepatic glucose output, inhibiting lipid accumulation (60, 61), reducing energy intake (62), and offering neuroprotective and cardiovascular benefits (63)
12 The REWIND trial evaluated dulaglutide in a broader population, including those with a lower baseline cardiovascular risk, and demonstrated a significant reduction in composite cardiovascular outcomes, together with a favourable trend in HF-related events
This comparison of bariatric surgery vs GLP-1 breaks down how surgical and medication-based approaches differ
95% CI, 0.77
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