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Ferroptosis is negatively regulated by the enzymatic activity of GPX4, and increasing attention to possible ways of inhibiting this cell death modality are needed ( In order to test if our new activator could have a beneficial effect in the context of inhibiting cell death, we evaluated compound 102 for its ability to prevent erastin-induced ferroptosis

[7] In a 2026 neuropathic-pain study, photoaffinity-probe experiments identified LanCL1 as a binding target of LAT8881-derived probe material in nervous-system models, and LanCL1 knockdown blocked the reported LAT8881 activity in those models

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Q10: What is AOD-9604's half-life