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To accommodate the upper half of the TMD pocket formed by ECL1 and the extracellular tips of TM1 and TM2 that diversified in both sequence and conformation across the three receptors, peptide 20 employs distinct barcodes (patterns of amino acids) to recognize specific region of a given receptor (Fig

Pharmacokinetics: Assessment of pharmacokinetic behavior in controlled research environments

rather, it induces an amino acid starvation response by upregulating the expression of SLC38A1, suggesting that SLC38A1 is a major importer of glutamine into these cells 90

2000, 15: 118-10.1002/(SICI)1098-1004(200001)15:1 3.0.CO;2-8