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In the STEP clinical trials with adults who had overweight or obesity, semaglutide 2.4 mg substantially reduced CRP levels compared to placebo, regardless of starting BMI or body weight

Insulin Secretion GLP-1 receptor agonists enhance insulin secretion in a glucose-dependent manner

Inventors: P.A.P., D.L.W., F.A., V.Z.P., S.Y.A., M.A

"We need more evidence to help these drugs be approved by regulatory agencies." Shah and his colleagues hope that with more clinical trials with bigger cohorts of patients, the research community will gather enough evidence to have this use of GLP-1s approved by the Food and Drug Administration and added into the American Diabetes Association standards of care for type 1