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The American Gastroenterological Association recommends starting with conservative dietary and lifestyle measures before progressing to pharmacological interventions
In adults with obesity who achieved weight loss on a low-calorie diet, adding liraglutide, a GLP-1 receptor agonist, plus regular moderate-to-vigorous exercise for one year further lowered metabolic syndrome severity and abdominal fat
Vidal J, Malkin SJP, Hunt B, Martin V, Hallen N, Ortega FJ
As a GLP-1 receptor agonist, semaglutide GLP-1 mimics the natural hormone glucagon-like peptide-1, crucial in appetite regulation
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