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The precise evaluation of growth status forms the basis of growth modification therapy in routine orthodontic practice and is essential as it reduces the burden for more complex treatment involving extractions and orthognathic surgeries

IGF-1 elevation persists for 9-11 days following a single dose

No analysis was conducted in the subgroup of patients with HF at baseline (approximately 14%) to determine whether treatment with liraglutide was associated with any change of severity of HF and/or cardiovascular mortality