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Additionally, improved glycemic control with GLP-1 RAs in T2DM patients may reduce glycosuria, a process known as glycemic buffering, which reduces caloric loss through urine and offsets part of the energy deficit induced by treatment [43,44,45]

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If you're taking other medications that reduce fluid intake or increase renal stresssuch as diuretics or NSAIDsyour PlexusDx provider may recommend a more conservative dose ceiling or closer monitoring intervals

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