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These drugs require dose titration, particularly to reduce adverse effects like nausea and diarrhea that are common soon after starting therapy, he says
Typically, patients must have a body mass index (BMI) of 30 or higher, or a BMI of 27 or higher with at least one obesity-related comorbidity, such as Type 2 diabetes, hypertension, or cardiovascular disease
These side effects can be intense enough for an estimated 10% to 20% of patients to stop using GLP-1s, and they tend to be dose dependent meaning that the higher the dose, the more intense or frequent the side effects can be
Azucena Herrera Chancay, M.D., Internal Medicine fellow
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