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The trial was a 52-week, open-label treat-to-target trial, which assessed the efficacy and safety of once-weekly IcoSema compared to once-daily insulin glargine U100 and insulin aspart (injected 2-4 times each day during mealtimes), dosed with or without oral glucoselowering medications
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Key points Oxalate homeostasis is maintained through a combination of endogenous biosynthesis, exogenous supply, and renal and faecal excretion
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