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Detection of reduced Glp1r expression in the livers of Glp1r Tie2/ mice (Figure 1C) prompted us to assess whether hepatic indices of metabolism or inflammation were differentially regulated in atherosclerosis-prone, PCSK9-AAVtreated, HFHC dietfed mice treated with or without semaglutide

Visualization of stained cells was achieved with tyramide-enhanced FITC or rhodamine (1:50 dilution in amplification solution

L.NamsathimaphornK.et al (2025)

By thoughtfully implementing combined approaches and carefully monitoring outcomes, forward-thinking clinicians can stay at the forefront of metabolic health management while providing comprehensive care that addresses multiple aspects of these complex conditions