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Glutathione and homoglutathione synthetases of legume nodules
HIFs are key transcriptional regulators mediating cellular adaptation to hypoxic environments [484], primarily regulating the expression of a series of oxygen-dependent genes [485]
Glutathione synthesis occurs in two ATP-dependent steps catalyzed by the enzymes gamma-glutamylcysteine ligase (GCL, the rate-limiting step) and glutathione synthetase [2]
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