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Serious side effects of these drugs include pancreatitis, hypoglycemia (low blood sugar), kidney failure, allergic reactions, thyroid tumors, and vision changes
BMI Reduction: Adolescents treated with semaglutide achieved a mean BMI reduction of 16.1%, compared with a 0.6% reduction in the placebo group
The 1.7mg dose was specifically studied in the STEP clinical trials as an intermediate maintenance option for people who experienced intolerable side effects at 2.4mg but wanted more effect than 1.0mg provided
Trends Pharmacol Sci 6:375378
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