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After initial repletion, a maintenance dose is given, often 1,000 mcg intramuscularly every month or every 2 to 3 months, to prevent recurrence of deficiency
A trial in 150 participants with either ovarian cancer or castration-resistant prostate cancer found no evidence that ALCAR (1g every 3 days) given with the anticancer drug sagopilone (for up to six cycles of treatment) reduced the overall risk of peripheral neuropathy compared to a placebo (90)
There are some long-term protocols with 30 days on, 1 week-off to ensure effectiveness
They allow adjustments to peptide concentrations, dosage, and formulations, making it easier to align the experiment design with specific research goals
