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Certain peptide-based medications have FDA-approved indications involving diabetes or chronic weight management
First, a little about gut peptides Lets start at the beginning
Blood-brain-barrier-penetrant AngIV analog Studied as a metabolically stabilized, orally active angiotensin-IV derivative designed to reach the brain in animal pharmacokinetic work
222 However, poor solubility and stability restrict its therapeutic application, necessitating the development of nanocarriers or other delivery strategies to improve bioavailability
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