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J Neurosci Res 66:755762

While semaglutide is generally well tolerated, it is most commonly associated with gastrointestinal symptoms such as nausea or diarrhea, especially during the early stages of treatment or when the dose is increased

Based on previous studies done in mice, researchers observed that GLP-1 agonists/DPP-4 inhibitors work to reduce inflammation in the gut, so they proposed that the same mechanism may occur in humans (5, 6)

This pattern is extremely common in ASD and is strongly associated with developmental delay, sensory overload, immune activation, gastrointestinal inflammation, and post-illness behavioral regression