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The effects appeared to rely on more than just improved in blood sugar control or weight reduction, the authors said, and suggest that metformin and GLP-1s might work directly on airway function to ease asthma
Once food passes through the gastrointestinal tract (GI), taste receptors, along with mechanosensors and chemoreceptors within the GI tract, transmit information via afferent branches of the vagus nerve and hormonal signaling (e.g., GLP-1, GIP, PYY, insulin, among others) (46)
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Further investigations of the relevant mechanisms have indicated that GLP-1 acts on bone tissue by promoting bone formation and inhibiting bone resorption
