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In summary, the importance of GLP-1R in the field of diabetes treatment is not only reflected in its precise regulation of blood glucose, but also in its ability to comprehensively manage multiple complications
Most of these trials measured endpoints like the status of antioxidant enzymes including GPx and inflammatory cytokines in the serum, reduction of radiotherapy side effects (like mucositis, myelosuppression, and diarrhea), and overall improvement of the quality of life
The risks of microdosing are significant and multifaceted: Therapeutic inefficacy : Sub-therapeutic doses may fail to achieve meaningful improvements in glycaemic control or weight management, potentially delaying appropriate treatment and allowing disease progression
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