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In addition to gastrointestinal symptoms, both Rybelsus and Ozempic carry a boxed warning due to the potential risk of thyroid C-cell tumors
10.1016/s1535-6108(0300050-3 26 DuJ.WangT.LiY.ZhouY.WangX.YuX.et al (2019)
Strengths of the present meta-analysis are the inclusion of all CVOTs published by 10 December 2021, the very large number of participants, the high quality of the trials which minimizes the risk of bias, and the absence of significant heterogeneity in most analyses, which ranged from absent to low or moderate
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