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Photoaging, a major component of extrinsic aging, induces notable structural changes in the skin, such as shortening and thickening of collagen fibers, damage to elastic fibers, loss of type I collagen, and alterations in the ratio of collagen types within the dermis
However, people with certain health conditions, such as kidney or heart problems, should consult a healthcare provider before treatment to ensure it is safe and appropriate
Thus, considering the quite rapid presentation of the beneficial effect of BPC 157 in wound healing, it is likely indicative that the expression of all of the genes Akt1, Braf, Egfr, Egr1, Grb2, Hdac7, Kras, Mapk1, Mapk3, Mapk14, Nos3, Pik3cd, Plcg1, Prkcg, Ptk2, Pxn, Src, Srf, and Vegfa is increased at the 10-min interval
It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive
