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165 In cancer, FOXOs exhibit dual behavior, either by suppressing tumor growth through autophagy activation or promoting survival under metabolic stress, depending on FOXO localization and the tumor context

High end: 40mg per kg

They may also benefit individuals experiencing metabolic slowdowns, stubborn fat, or weight-loss plateaus despite consistent nutrition and exercise efforts

Eligible patients (N=135) between the ages of 10-17 years had A1C levels between 7%-11% if they were being treated with diet and exercise alone or between 6.5%-11% if they were being treated with metformin (with or without insulin) and had a body mass index (BMI) greater than the 85th percentile