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Oxidative stress can increase as a result of illness, environmental toxins, poor diet and other lifestyle factors
Destruction of the thyroid and ovaries may be caused by greater exposure to autoantibodies, and the consequence of both disorders may be insulin resistance, impaired glucose tolerance, weight gain, and infertility
Engineered IGF-1 analogs with reduced IGF-binding-protein affinity (research)
It also improves immunological function
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