Other processes that require ascorbic acid include biosynthesis of corticosteroids and aldosterone, proteins, neuropeptides, and carnitine
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Myocardial remodelling characterized by fibrosis and hypertrophy, impaired microcirculation, abnormal protein function caused by advanced glycation end products, changes in myocardial metabolism and abnormal mitochondrial function have been noted as associated factors of diabetic cardiomyopathy [14]
While western blot analyses or ELISAs can accurately determine the abundance of the LPL protein, this does not consider the presence or absence of activating (e.g., ApoC-II and ApoA-V), inhibiting (e.g., Angptl4, ApoC-I, and ApoC-III) factors, whether LPL has been unfolded, or is in an inactive state