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In general, GLP-1s act on various organs in the body, including the gut, pancreas, and brain, to affect blood sugar response and appetite
Neither mechanism directly stimulates insulin secretion in a glucose-independent manner, making the combination inherently safer regarding hypoglycaemia compared to sulphonylureas or insulin
From a systems biology point of view, the oxidative load must first be reduced before recovery becomes visible
This is particularly helpful for patients who have undergone bariatric surgery or lost massive amounts of weight
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