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Given the observation that the effects of PNKP, MRVI1, and INPP5B loci on migraine risk were opposite at the gene expression and protein expression levels, we used MR analysis to assess the causal relationship between gene expression and protein levels

Recent studies have revealed that difficulty sleeping, one of the five symptoms scored for AMS, is more of an effect of hypoxia than closely related to other AMS symptoms, thereby removing the sleep component from the Lake Louise AMS score in 2018