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NADPH is also used in the processes of cellular protection against redox stress by providing reducing equivalents to antioxidants such as glutathione and thioredoxin
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Supporting that pool is thought to be relevant to mitochondrial efficiency a connection that overlaps with the broader longevity and cellular health research base
It is thought that stages 2 and 3 should be targeted with prophylactic therapies, such as lipid lowering drugs or RAS modifiers [13], to minimize the progression of CKD
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