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Description

Helsinn Healthcare conducted clinical development for postoperative GI motility (ipamorelin was investigated as a GI prokinetic given its partial GI tract action through peripheral GHSR-1a), but no NDA was filed

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This concern may have stemmed from a study that looked at post-marketing FDA adverse event reports from exenatide and sitagliptin usage from 2004-2009

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Under 18's & over 60's, as results are likely not to be effective

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Science2005 Feb 18;307(5712):1098-101

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