In a zebrafish model, compared with C3-carnitine, C18-carnitine and C18:1-carnitine can induce the inhibition of OXPHOS, interfere with the energy supply of cardiomyocytes, and lead to a significant impairment of cardiac systolic function, which manifests as a decreased heart rate and reduced shortening of the atrial and ventricular fractions [21]
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This triple-action mechanism makes it a subject of intense interest in metabolic research
Challenges, direction for further research, and concluding remarks Since the term eryptosis was coined in 2005 by a group of researchers from the University of Tbingen (Germany) led by Florian Lang [24], a steady and continuous stream of novel papers focusing on eryptosis has been observed
