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Availability, regulatory status, and supply chain reliability all play into the practical calculus of choosing between them
Most common are mild discomfort at the injection site
Additional sources of PUFAs for lipid peroxidation include the peroxisome-mediated biosynthesis of plasmalogens through TMEM189 (transmembrane protein 189) in human ovarian and kidney cancer cell lines [93, 94] and lipophagy-mediated lipid droplet degradation in human liver cancer cell lines [95, 96], although the initiation signals for these alternative pathways are not well understood
Result: p53 nuclear exclusion, mitochondrial translocation, and apoptosis
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