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Studies in Crat knockout mice demonstrated that CrAT deficiency leads to abnormal fuel selection, which results in a perturbation of glucose homeostasis and suggest that deficits in CrAT activity might contribute to diet-induced metabolic inflexibility by exacerbating the Randle glucose-fatty acid cycle 66

Large-scale human trials evaluating lifespan, disease prevention, or long-term aging outcomes do not currently exist

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For accessibility, COAs are lot-specific, uniquely identified by batch numbers printed on product vials, and readily accessible through the Lab Tests page on our website