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In acetaminophen-induced liver injury, excessive lipid peroxidation, GSH depletion, GPX4 suppression, increased LC3II expression, p62 degradation and autophagosomes accumulation were observed in hepatic cells, which are in accordance with the typical features of ferroptosis and autophagy, respectively

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Basic-science research suggests citrulline can steer macrophages toward an anti- inflammatory phenotype, but no clinical trials have evaluated immune outcomes with Bi- Amino Injection

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