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The enzyme is located primarily in the peroxisomes but absent in mitochondria of mammalian cells
In both studies, tesamorelin-treated patients completing the 26-week treatment period were re-randomized to blinded therapy with either daily placebo or 2 mg tesamorelin for an additional 26-week treatment period (Extension Phase) in order to assess maintenance of VAT reduction and to gather long-term safety data
The SDH enzyme plays an essential role in tumor suppression
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