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"Centenarians display plasma MOTS-c concentrations significantly higher than age-matched peers, a pattern that closely resembles levels found in individuals decades younger suggesting preserved mitochondrial signaling as a hallmark of exceptional longevity." The connection to cellular senescence deserves further attention here

Wait until initial pain and inflammation decrease (typically week 2-3 of treatment) before beginning progressive loading protocols

The numbers are accurate, but they are only safe inside a clinical relationship that screens you, supervises you, and adjusts when your physiology calls for it

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