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Obeticholic acid (Intercept Pharmaceuticals), Cenicriviroc (Allergan), Aramchol (Galmed Pharmaceuticals), Resmetirom (Madrigal Pharmaceuticals), Dapagliflozin and Semaglutide (Novo Nordisk) are in advanced Phase 3 clinical trials, while Belapectin (Galectin Therapeutics), MSDC-0602K (Cirius Therapeutics), Lanifibranor (Inventiva), Efruxifermin (Akero) and Tesamorelin (Theratechnologies) are expected to start Phase 3 trials soon
10.1093/hmg/3.10.1757 113 FinelliM
Fatigue or feeling off while the body adjusts
In contrast, long-acting GLP-1RA has a less pronounced effect on gastric emptying over time due to tachyphylaxis [72] but yields more significant and consistent weight loss [71]
