This helps explain why semaglutide might be linked to acne
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An observational study published in the BMJ in 2016 found no increased risk of breast cancer among GLP-1 analog users when compared to DPP-4 inhibitor users (HR 1.40 (95%CI [0.91 to 2.16])
To identify baseline characteristics for inclusion in the CV risk prediction model, a set of characteristics known to be important (or potentially important) predictors of CV risk, common to both LEADER and the pooled semaglutide randomized controlled trials (RCTs), were considered in a Cox proportional hazard model with stepwise selection using SAS PHREG (SAS, 2019)