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Moreover, the overexpression of COX-2 is often closely associated with chemotherapy resistance and immune escape processes in tumors, suggesting that COX-2 is an attractive therapeutic target in tumors (107)

In addition to its principal activity in islet cells, ghrelin inhibits gastric secretion and gastrointestinal motility, delays gastric emptying, increases satiety and decreases food intake in gastrointestinal tissues (Brubaker and Drucker, 2002)

Understanding how peptides degrade allows researchers to design more stable drug formulations and determine appropriate storage conditions

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