According to the FDA's official guidance (updated April 2026 at fda.gov), the semaglutide injection shortage was resolved on February 21, 2025, and the transitional exemption windows for compounders operating under the shortage exemption subsequently ended - for 503A pharmacies by April 22, 2025, and for 503B outsourcing facilities by May 22, 2025
And as more people take the meds, doctors and patients alike are noticing many more unexpected benefits beyond the quieting of food noise
The peptide sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) remains stable in gastric acid, which distinguishes it from many other growth factors and healing compounds that degrade rapidly in the digestive system
However, by lowering blood glucose and reducing appetite, Semaglutide may mask some side effects of steroids, making it harder to notice steroid-related changes