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Oxidative Stress: Pathogenetic role in diabetes mellitus and its complications and therapeutic approaches to correction
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Research by Berlanga-Acosta and colleagues documented that GHRP-6 reduced myocardial necrosis in animal models of acute myocardial infarction, with protective effects that appear to be mediated in part through CD36 receptor binding, a secondary receptor pathway independent of the GHS-R1a/GH axis
At the currently approved maximum dose of 14mg, the PIONEER clinical trials showed weight loss of approximately 4-5kg (about 4-5% of body weight) over 26 weeks in patients with type 2 diabetes
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