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Expect initial GI side effects to potentially worsen endometriosis symptoms before improvement occurs
This coincided with the appearance of anonymous and famous users (Elon Musk is one of them) who shared videos on platforms such as Instagram or TikTok in which they boasted about how a simple injection had helped them lose weight under tags such as #MyOzempicJourney
What they found: No serious adverse events triggered by AOD-9604 The most frequent side effects: headache (~5 %), occasional fatigue, at the same frequency as placebo No changes in IGF-1 levels, glycemia, blood pressure, heart rate No signals of cardiovascular, hepatic or renal toxicity Safety profile comparable to placebo Why it matters: From a safety perspective, AOD-9604 is one of the safest peptides in the clinical registry
FASEB J 19:15046, PMID: 15972297 Kanno T, Nishizaki T (2001) Sphingosine induces apoptosis in hippocampal neurons and astrocytes by activating caspase-3/-9 via a mitochondrial pathway linked to SDK/14-3-3 protein/Bax/cytochrome c
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