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It is no coincidence that melatonin, in addition to having a plethora of beneficial effects, executes neuroprotection by modulating mPTP activity 49,50
These results may inform research into psychiatric safety and potential repurposing opportunities for GLP-1RAs, especially in people with mental health disorders, but randomized clinical trials are needed to determine whether the genetic associations translate into treatment benefits
Dietary changes Avoid spicy and fatty foods Avoid spicy, fried, or high-fat foods as they can trigger or worsen reflux symptoms
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