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Lean C57BL/6J mice and genetically obese (ob/ob) mice, all 12 weeks old, were divided into three treatment groups including: saline control, AOD9604 at a dose of 250 g/kg/day, and hGH at a dose of 1 mg/kg/day, with each group consisting of six mice

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American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity